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<i>Thujopsis dolabrata<_i> (Thunberg ex L. f.) Sieb. et Zucc.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) Cannabinoid Receptor (1) Fungal (1) HIF/HIF Prolyl-Hydroxylase (1) Integrin (1) Microtubule/Tubulin (1) NF-κB (3) p38 MAPK (2) Phosphatase (1) TNF Receptor (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0263

Toosendanin 4 Publications Verification	Others	Inflammation/Immunology
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .

HY-N2247

Guaiacin	Phosphatase	Metabolic Disease
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .

HY-N2394

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Others	Inflammation/Immunology
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC₅₀ of 0.85 μM .

HY-N6930

Shikonofuran A	Others	Metabolic Disease
Shikonofuran A is a natural product isolated from the root of Lithosperraum erythrorhizon Sieb.

HY-N11030

Futoamide	Others	Others
Futoamide is an active compound. Futoamide can be isolated from Piper futokadzura SIEB. et ZUCC .

HY-N8919

N-trans-Sinapoyltyramine	Others	Others
N-trans-Sinapoyltyramine is an alkaloid. N-trans-Sinapoyltyramine can be isolated from Lindera glauca Sieb Zucc .

HY-N8298

Taxezopidine L	Others	Others
Taxezopidine L is a Diterpenoids product that can be isolated from the seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc. .

HY-N7467

Taxuspine X	Others	Others
Taxuspine X is a Diterpenoids product that can be isolated from the stems of the Japanese yew Taxus cuspidata Sieb. et Zucc. .

HY-N8292

7-(2'-Deoxyadenosin-N6-yl)aristolactam I	Others	Others
7-(2'-Deoxyadenosin-N6-yl)aristolactam I is a Alkaloids product that can be isolated from the herbs of Aristolochia debilis Sieb. et Zucc .

HY-122960

Epifriedelanol acetate	Cannabinoid Receptor	Others
Epifriedelanol acetate (Compound Ⅲc) is a nature product. Epifriedelanol acetate can be isolated from Pachysandra terminalis Sieb .

HY-N5112B

β,β-Dimethylacrylshikonin 1 Publications Verification Isoarnebin I	HIF/HIF Prolyl-Hydroxylase	Cancer
β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Lithospermum erythrorhizon Sieb. et Zucc. , promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity .

HY-N0631

Cornuside 2 Publications Verification	p38 MAPK NF-κB	Inflammation/Immunology
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-N0631R

Cornuside (Standard)	p38 MAPK NF-κB	Inflammation/Immunology
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-107237

Broussonetine A	Others	Others
Broussonetine A is a pyrrolidine alkaloid compound isolated from the branches of Broussonetia kazinoki Sieb .

HY-N8956

Pachysamine M	Others	Others
Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc .

HY-N7756

2-Deacetoxydecinnamoyltaxinine J	Others	Others
2-Deacetoxydecinnamoyltaxinine J is an active compound that can be isolated from Taxus cuspidta Sibe et Zucc .

HY-N4164

Schinifoline	Apoptosis	Cancer
Schinifoline, a 4-quinolinone derivative isolated from Zanthoxylum schinifolium Sieb, improves radiosensitizing effect, and effects cell cycle and apoptotic-inducing effects in cancer .

HY-N8903

Mumefural	Integrin NF-κB Toll-like Receptor (TLR) TNF Receptor	Cardiovascular Disease Neurological Disease
Mumefural is a bioactive component of the processed fruit of Prunus mume Sieb. Mumefural inhibits platelet aggregation. Mumefural shows anti-thrombotic effects and ameliorates cognitive impairment .

HY-N2082

Isorhamnetin 3-O-galactoside 1 Publications Verification Cacticin	Others	Cardiovascular Disease Inflammation/Immunology
Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities .

HY-N1300

Shizukanolide F	Fungal	Infection Cancer
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

HY-W127616A

β-Sitosterol acetate, 95% Sitosteryl acetate, 95%	Bacterial	Infection
β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .

HY-N1391

10-Deacetyltaxol 10-Deacetylpaclitaxel	Microtubule/Tubulin	Cancer
10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

Cat. No.	Product Name	Type

HY-W127616A

β-Sitosterol acetate, 95% Sitosteryl acetate, 95%	Biochemical Assay Reagents
β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .

Toosendanin 4 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Melia toosendan Sieb. et Zucc. Plants Meliaceae Inflammation/Immunology Disease Research Fields	Others
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .

Guaiacin	Zingiber officinale Roscoe Structural Classification Classification of Application Fields Source classification Lignans Phenols Polyphenols Metabolic Disease Phenylpropanoids Plants Disease Research Fields Zingiberaceae	Phosphatase
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .

Emodin-1-O-β-D-glucopyranoside 1 Publications Verification	Quinones Structural Classification Rheum palmatum L. Classification of Application Fields Anthraquinones Polygonaceae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Others
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC₅₀ of 0.85 μM .

Shikonofuran A	Natural Products Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Lithospermum canescens Lehm. Disease Research Fields Boraginaceae	Others
Shikonofuran A is a natural product isolated from the root of Lithosperraum erythrorhizon Sieb.

Futoamide	Structural Classification Simple Phenylpropanols Source classification Piper kadsura Piperaceae Phenylpropanoids Plants	Others
Futoamide is an active compound. Futoamide can be isolated from Piper futokadzura SIEB. et ZUCC .

N-trans-Sinapoyltyramine	Structural Classification Source classification Phenols Polyphenols Plants Lauraceae Lindera glauca (Siebold & Zucc.) Blume	Others
N-trans-Sinapoyltyramine is an alkaloid. N-trans-Sinapoyltyramine can be isolated from Lindera glauca Sieb Zucc .

Taxezopidine L	Structural Classification Taxus cuspidata Siebold & Zucc. Terpenoids Taxaceae Source classification Diterpenoids Plants	Others
Taxezopidine L is a Diterpenoids product that can be isolated from the seeds of the Japanese yew Taxus cuspidata Sieb. et Zucc. .

Taxuspine X	Structural Classification Japanese yew Taxus cuspidata Sieb. et Zucc. Terpenoids Taxaceae Source classification Diterpenoids Plants	Others
Taxuspine X is a Diterpenoids product that can be isolated from the stems of the Japanese yew Taxus cuspidata Sieb. et Zucc. .

7-(2'-Deoxyadenosin-N6-yl)aristolactam I	Structural Classification Alkaloids Aristolochia debilis Siebold & Zucc. Other Alkaloids Source classification Plants Aristolochiaceae	Others
7-(2'-Deoxyadenosin-N6-yl)aristolactam I is a Alkaloids product that can be isolated from the herbs of Aristolochia debilis Sieb. et Zucc .

Epifriedelanol acetate	Triterpenes Structural Classification Buxaceae Terpenoids Source classification Pachysandra terminalis Siebold & Zucc. Plants	Cannabinoid Receptor
Epifriedelanol acetate (Compound Ⅲc) is a nature product. Epifriedelanol acetate can be isolated from Pachysandra terminalis Sieb .

β,β-Dimethylacrylshikonin 1 Publications Verification Isoarnebin I	Quinones Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Plants Lithospermum erythrorhizon Sieb. et Zucc. Naphthalene Quinones Disease Research Fields Boraginaceae Cancer	HIF/HIF Prolyl-Hydroxylase
β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Lithospermum erythrorhizon Sieb. et Zucc. , promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity .

Cornuside 2 Publications Verification	Structural Classification Iridoids Cornaceae Classification of Application Fields Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	p38 MAPK NF-κB
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

Cornuside (Standard)	Structural Classification Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Phenols Polyphenols Plants	p38 MAPK NF-κB
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

Broussonetine A	Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Plants Moraceae Broussonetia kazinoki Sieb. et Zucc. Disease Research Fields	Others
Broussonetine A is a pyrrolidine alkaloid compound isolated from the branches of Broussonetia kazinoki Sieb .

Pachysamine M	Structural Classification Alkaloids Buxaceae Other Alkaloids Source classification Pachysandra terminalis Siebold & Zucc. Plants	Others
Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc .

2-Deacetoxydecinnamoyltaxinine J	Structural Classification Natural Products Source classification Taxaceae Plants Taxus wallichiana Zucc.	Others
2-Deacetoxydecinnamoyltaxinine J is an active compound that can be isolated from Taxus cuspidta Sibe et Zucc .

Schinifoline	Zanthoxylum bungeanum Maxim. Alkaloids Classification of Application Fields Source classification Rutaceae Quinoline Alkaloids Plants Disease Research Fields Cancer	Apoptosis
Schinifoline, a 4-quinolinone derivative isolated from Zanthoxylum schinifolium Sieb, improves radiosensitizing effect, and effects cell cycle and apoptotic-inducing effects in cancer .

Isorhamnetin 3-O-galactoside 1 Publications Verification Cacticin	Cardiovascular Disease Flavonols Flavonoids Classification of Application Fields Typhaceae Source classification Typha angustifolia L. Phenols Polyphenols Plants Disease Research Fields	Others
Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated from Artemisia capillaris Thunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory signaling pathways. Isorhamnetin 3-O-galactoside (Cacticin) has antithrombotic and anti-inflammatory activities .

Shizukanolide F	Structural Classification Chloranthus serratus (Thunb.) Roem. et Schult. Terpenoids Sesquiterpenes Source classification Chloranthaceae Plants	Fungal
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer .

10-Deacetyltaxol 10-Deacetylpaclitaxel	Structural Classification Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus wallichiana Zucc. Cancer	Microtubule/Tubulin
10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

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<i>Thujopsis dolabrata<_i> (Thunberg ex L. f.) Sieb. et Zucc.

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